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Articles (42)
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The IL-27 Receptor Has Biphasic Effects in Crescentic Glomerulonephritis Mediated Through Th1 Responses

Shaun A. Summers, Richard K.S. Phoon, Joshua D. Ooi, Stephen R. Holdsworth, A. Richard Kitching

Journal:

The American Journal of Pathology

Année:

2011

Langue:

english

Fichier:

PDF, 3.61 MB

english, 2011

Toll-like receptor 2 induces Th17 myeloperoxidase autoimmunity while Toll-like receptor 9 drives Th1 autoimmunity in murine vasculitis

Shaun A. Summers, Oliver M. Steinmetz, Poh-Yi Gan, Joshua D. Ooi, Dragana Odobasic, A. Richard Kitching, Stephen R. Holdsworth

Journal:

Arthritis & Rheumatism

Année:

2011

Langue:

english

Fichier:

PDF, 785 KB

english, 2011

Review: T helper 17 cells: Their role in glomerulonephritis

JOSHUA D OOI, A RICHARD KITCHING, STEPHEN R HOLDSWORTH

Journal:

Nephrology

Année:

2010

Langue:

english

Fichier:

PDF, 223 KB

english, 2010

The isolation and purification of biologically active recombinant and native autoantigens for the study of autoimmune disease

Jim Apostolopoulos, Joshua D.K. Ooi, Dragana Odobasic, Stephen R. Holdsworth, A. Richard Kitching

Journal:

Journal of Immunological Methods

Année:

2006

Langue:

english

Fichier:

PDF, 257 KB

english, 2006

Renal Dendritic Cells Adopt a Pro-Inflammatory Phenotype in Obstructive Uropathy to Activate T Cells but Do Not Directly Contribute to Fibrosis

Sarah L. Snelgrove, Joshua Y. Kausman, Cecilia Lo, Camden Lo, Joshua D. Ooi, P. Toby Coates, Michael J. Hickey, Stephen R. Holdsworth, Christian Kurts, Daniel R. Engel, A. Richard Kitching

Journal:

The American Journal of Pathology

Année:

2012

Langue:

english

Fichier:

PDF, 4.24 MB

english, 2012

Advances in the pathogenesis of Goodpasture's disease: From epitopes to autoantibodies to effector T cells

Joshua D. Ooi, Stephen R. Holdsworth, A. Richard Kitching

Journal:

Journal of Autoimmunity

Année:

2008

Langue:

english

Fichier:

PDF, 241 KB

english, 2008

Toll-Like Receptor 9 Enhances Nephritogenic Immunity and Glomerular Leukocyte Recruitment, Exacerbating Experimental Crescentic Glomerulonephritis

Shaun A. Summers, Oliver M. Steinmetz, Joshua D. Ooi, Poh-yi Gan, Kim M. O'Sullivan, Kumar Visvanathan, Shizuo Akira, A. Richard Kitching, Stephen R. Holdsworth

Journal:

The American Journal of Pathology

Année:

2010

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2010

Alterations in Type I and III Collagen Turnover in Patients with Acute Decompensated Heart Failure

Mark Fisch, Joshua Balog, Tania Chao, Flora Sam, Henry Ooi, Deborah Siwik, Wilson Colucci

Journal:

Journal of Cardiac Failure

Année:

2006

Langue:

english

Fichier:

PDF, 65 KB

english, 2006

Mast cell activation and degranulation promotes renal fibrosis in experimental unilateral ureteric obstruction

Summers, Shaun A, Gan, Poh-yi, Dewage, Lakshi, Ma, Frank T, Ooi, Joshua D, O'Sullivan, Kim M, Nikolic-Paterson, David J, Kitching, A Richard, Holdsworth, Stephen R

Journal:

Kidney International

Année:

2012

Langue:

english

Fichier:

PDF, 648 KB

english, 2012

Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus

Devi, Sapna, Li, Anqi, Westhorpe, Clare L V, Lo, Camden Y, Abeynaike, Latasha D, Snelgrove, Sarah L, Hall, Pam, Ooi, Joshua D, Sobey, Christopher G, Kitching, A Richard, Hickey, Michael J

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2012

Myeloperoxidase (MPO)-specific CD4+ T cells contribute to MPO-anti-neutrophil cytoplasmic antibody (ANCA) associated glomerulonephritis

Gan, Poh-Yi, Holdsworth, Stephen R., Kitching, A. Richard, Ooi, Joshua D.

Journal:

Cellular Immunology

Année:

2013

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2013

Recurrent Multi-Organism Keratoconjunctivitis Manifesting as a First Presentation of Common Variable Immune Deficiency (CVID)

Ooi, Kenneth G.-J., Joshua, Fredrick, Broadfoot, Andrew

Journal:

Ocular Immunology & Inflammation

Année:

2007

Langue:

english

Fichier:

PDF, 72 KB

english, 2007

Endogenous foxp3+ T-regulatory cells suppress anti-glomerular basement membrane nephritis

Ooi, Joshua D, Snelgrove, Sarah L, Engel, Daniel R, Hochheiser, Katharina, Ludwig-Portugall, Isis, Nozaki, Yuji, O'Sullivan, Kim M, Hickey, Michael J, Holdsworth, Stephen R, Kurts, Christian, Kitching

Journal:

Kidney International

Année:

2011

Langue:

english

Fichier:

PDF, 950 KB

english, 2011

FcγRIIB regulates T-cell autoreactivity, ANCA production, and neutrophil activation to suppress anti-myeloperoxidase glomerulonephritis

Ooi, Joshua D, Gan, Poh-Yi, Chen, Tong, Eggenhuizen, Peter J, Chang, Janet, Alikhan, Maliha A, Odobasic, Dragana, Holdsworth, Stephen R, Kitching, A Richard

Journal:

Kidney International

Année:

2014

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2014

Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis

Summers, Shaun A, van der Veen, Betty S, O'Sullivan, Kim M, Gan, Poh-Yi, Ooi, Joshua D, Heeringa, Peter, Satchell, Simon C, Mathieson, Peter W, Saleem, Moin A, Visvanathan, Kumar, Holdsworth, Stephen

Journal:

Kidney International

Année:

2010

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2010

CD4+ Th1 cells are effectors in lupus nephritis—but what are their targets?

Ooi, Joshua D, Kitching, A Richard

Journal:

Kidney International

Année:

2012

Langue:

english

Fichier:

PDF, 162 KB

english, 2012

Corrigendum: Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus

Devi, Sapna, Li, Anqi, Westhorpe, Clare L V, Lo, Camden Y, Abeynaike, Latasha D, Snelgrove, Sarah L, Hall, Pam, Ooi, Joshua D, Sobey, Christopher G, Kitching, A Richard, Hickey, Michael J

Journal:

Nature Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 106 KB

english, 2016

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

Marceau, Caleb D., Puschnik, Andreas S., Majzoub, Karim, Ooi, Yaw Shin, Brewer, Susan M., Fuchs, Gabriele, Swaminathan, Kavya, Mata, Miguel A., Elias, Joshua E., Sarnow, Peter, Carette, Jan E.

Journal:

Nature

Année:

2016

Langue:

english

Fichier:

PDF, 8.44 MB

english, 2016

Analysis of bulk heterojunction material parameters using lateral device structures

Danielson, Eric, Ooi, Zi-En, Liang, Kelly, Morris, Joshua, Lombardo, Christopher, Dodabalapur, Ananth

Journal:

Journal of Photonics for Energy

Année:

2014

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2014

Programmed death 1 and its ligands do not limit experimental foreign antigen-induced immune complex glomerulonephritis

Ooi, Joshua D, Li, Ming, Kourkoutzelos, Katerina, Yagita, Hideo, Azuma, Miyuki, Holdsworth, Stephen R, Kitching, A Richard

Journal:

Nephrology

Année:

2015

Langue:

english

Fichier:

PDF, 559 KB

english, 2015

The NLRP3 inflammasome in kidney disease and autoimmunity

Hutton, Holly L, Ooi, Joshua D, Holdsworth, Stephen R., Kitching, A. Richard

Journal:

Nephrology

Année:

2016

Langue:

english

Fichier:

PDF, 424 KB

english, 2016

From bench to pet shop to bedside? The environment and immune function in mice

Kitching, A. Richard, Ooi, Joshua D.

Journal:

Kidney International

Année:

2016

Langue:

english

Fichier:

PDF, 226 KB

english, 2016

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells

Ooi, Joshua D., Petersen, Jan, Tan, Yu H., Huynh, Megan, Willett, Zoe J., Ramarathinam, Sri H., Eggenhuizen, Peter J., Loh, Khai L., Watson, Katherine A., Gan, Poh Y., Alikhan, Maliha A., Dudek, Nadin

Journal:

Nature

Année:

2017

Langue:

english

Fichier:

PDF, 6.92 MB

english, 2017

Pathogenic Role for γδ T Cells in Autoimmune Anti-Myeloperoxidase Glomerulonephritis

Gan, Poh-Yi, Fujita, Takeshi, Ooi, Joshua Daniel, Alikhan, Maliha Asghar, Dick, Jonathan, Shim, Raymond, Odobasic, Dragana, O’Sullivan, Kim Maree, Kitching, Arthur Richard, Holdsworth, Stephen Roger

Journal:

The Journal of Immunology

Année:

2017

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2017

C5a receptor 1 promotes autoimmunity, neutrophil dysfunction and injury in experimental anti-myeloperoxidase glomerulonephritis

Dick, Jonathan, Gan, Poh-Yi, Ford, Sharon L., Odobasic, Dragana, Alikhan, Maliha A., Loosen, Sven H., Hall, Pam, Westhorpe, Clare L., Li, Anqi, Ooi, Joshua D., Woodruff, Trent M., Mackay, Charles R.,

Journal:

Kidney International

Année:

2017

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2017

Renal Dendritic Cells: The Long and Winding Road

Kitching, A. Richard, Ooi, Joshua D.

Journal:

Journal of the American Society of Nephrology

Année:

2017

Langue:

english

Fichier:

PDF, 639 KB

english, 2017

Regulatory T cells in renal disease

Alikhan, Maliha A, Huynh, Megan, Kitching, A Richard, Ooi, Joshua D

Journal:

Clinical & Translational Immunology

Année:

2018

Langue:

english

Fichier:

PDF, 310 KB

english, 2018

Role of outpatient parenteral antibiotic therapy in the treatment of community acquired skin and soft tissue infections in Singapore

Chan, Monica, Ooi, Chee Kheong, Wong, Joshua, Zhong, Lihua, Lye, David

Journal:

BMC Infectious Diseases

Année:

2017

Langue:

english

Fichier:

PDF, 357 KB

english, 2017

HLA and kidney disease: from associations to mechanisms

Robson, Kate J., Ooi, Joshua D., Holdsworth, Stephen R., Rossjohn, Jamie, Kitching, A. Richard

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Année:

2018

Langue:

english

Fichier:

PDF, 2.40 MB

english, 2018

The Relationship Between Clinical and Indocyanine Green Staging in Lymphedema

Garza, Rebecca M., Ooi, Adrian S.H., Falk, Joshua, Chang, David W.

Journal:

Lymphatic Research and Biology

Année:

2018

Langue:

english

Fichier:

PDF, 145 KB

english, 2018

HLA-DR15-specific inhibition attenuates autoreactivity to the Goodpasture antigen

Huynh, Megan, Eggenhuizen, Peter J., Olson, Gary L., Rao, N. Bhaskara, Self, Christopher R., Sun, Yanjun, Holdsworth, Stephen R., Kitching, A. Richard, Ooi, Joshua D.

Journal:

Journal of Autoimmunity

Année:

2019

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2019

Dominant protection from HLA-mediated autoimmune disease is conferred by antigen specific regulatory T cells

Ooi, Joshua D., Petersen, Jan, Tan, Yu H., Huynh, Megan, Willett, Zoe J., Dudek, Nadine L., Eggenhuizen, Peter J., Loh, Khai L., Watson, Katherine A., Gan, Poh-Y., Handel, Andreas, Hudson, Billy G., F

Journal:

Pathology

Année:

2018

Fichier:

PDF, 72 KB

2018

Biologicals targeting T helper cell subset differentiating cytokines are effective in the treatment of murine anti-myeloperoxidase glomerulonephritis.

Gan, Poh-Yi., Chan, Amy, Ooi, Joshua. D., Dick, Jonathan., Nagai, Kei., O’Sullivan, Kim. M., Oudin, Virginie., Shim, Raymond., Kitching, A. Richard., Holdsworth, Stephen. R.

Journal:

Kidney International

Année:

2019

Langue:

english

Fichier:

PDF, 7.74 MB

english, 2019

Biologicals targeting T helper cell subset differentiating cytokines are effective in the treatment of murine anti-myeloperoxidase glomerulonephritis.

Gan, Poh-Yi., Chan, Amy, Ooi, Joshua. D., Dick, Jonathan., Nagai, Kei., O’Sullivan, Kim. M., Oudin, Virginie., Shim, Raymond., Kitching, A. Richard., Holdsworth, Stephen. R.

Journal:

Kidney International

Année:

2019

Fichier:

PDF, 7.74 MB

2019

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

Ooi, Joshua D., Jiang, Jhih-Hang, Eggenhuizen, Peter J., Chua, Ling L., van Timmeren, Mirjan, Loh, Khai L., O’Sullivan, Kim M., Gan, Poh Y., Zhong, Yong, Tsyganov, Kirill, Shochet, Lani R., Ryan, Jess

Journal:

Nature Communications

Année:

2019

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2019

Apoptotic Cell–Induced, Antigen-Specific Immunoregulation to Treat Experimental Antimyeloperoxidase GN

Gan, Poh-Yi, Godfrey, Andrea S., Ooi, Joshua D., O’Sullivan, Kim-Maree, Oudin, Virginie, Kitching, A. Richard, Holdsworth, Stephen R.

Journal:

Journal of the American Society of Nephrology

Année:

2019

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2019

Seagrass‐associated fungal communities show distance decay of similarity that has implications for seagrass management and restoration

Wainwright, Benjamin J., Zahn, Geoffrey L., Zushi, Joshua, Lee, Nicole Li Ying, Ooi, Jillian Lean Sim, Lee, Jen Nie, Huang, Danwei

Journal:

Ecology and Evolution

Année:

2019

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2019

Seagrass‐associated fungal communities show distance decay of similarity that has implications for seagrass management and restoration

Wainwright, Benjamin J., Zahn, Geoffrey L., Zushi, Joshua, Lee, Nicole Li Ying, Ooi, Jillian Lean Sim, Lee, Jen Nie, Huang, Danwei

Journal:

Ecology and Evolution

Année:

2019

Fichier:

PDF, 1.22 MB

2019

Risk factors for treatment resistance and relapse of Chinese patients with MPO-ANCA-associated vasculitis

Huang, Li, Shen, Chanjuan, Zhong, Yong, Ooi, Joshua D., Zhou, Ya-Ou, Chen, Jin-Biao, Wu, Ting, Meng, Ting, Xiao, Zhou, Lin, Wei, Ao, Xiang, Xiao, Xiangcheng, Zhou, Qiaoling, Xiao, Ping

Journal:

Clinical and Experimental Medicine

Année:

2020

Langue:

english

Fichier:

PDF, 605 KB

english, 2020

The association of neutrophil-to-lymphocyte ratio with all-cause mortality in Chinese patients with MPO-ANCA associated vasculitis

Huang, Li, Shen, Chanjuan, Zhong, Yong, Ooi, Joshua D., Zhou, Ya-Ou, Chen, Jin-Biao, Wu, Ting, Meng, Ting, Xiao, Zhou, Lin, Wei, Ao, Xiang, Tang, Rong, Xiao, Xiangcheng, Zhou, Qiaoling, Xiao, Ping

Journal:

Clinical and Experimental Medicine

Année:

2020

Fichier:

PDF, 1.06 MB

2020

Treg Enhancing Therapies to Treat Autoimmune Diseases

Eggenhuizen, Peter J., Ng, Boaz H., Ooi, Joshua D.

Journal:

International Journal of Molecular Sciences

Année:

2020

Fichier:

PDF, 1.76 MB

2020

Risk prediction models to guide antibiotic prescribing: a study on adult patients with uncomplicated upper respiratory tract infections in an emergency department

Wong, Joshua Guoxian, Aung, Aung-Hein, Lian, Weixiang, Lye, David Chien, Ooi, Chee-Kheong, Chow, Angela

Journal:

Antimicrobial Resistance and Infection Control

Année:

2020

Fichier:

PDF, 1.90 MB

2020